TOBI is taken twice a day in a 28-day-on/28-day-off cycle.
TOBI® (Tobramycin Inhalation Solution, USP)
should be taken twice a day in a cycle of 28 days on and 28 days off.
After 28 days of taking TOBI, take a 28-day break.
Here are other guidelines to follow when taking TOBI:
Doses of TOBI should be taken as close to 12 hours apart as possible, and should not be taken less than 6 hours apart
Taking TOBI requires about 15-20 minutes of nebulization time, assuming a clean and working nebulizer
and compressor are used
The time it takes to nebulize
is different for every TOBI patient. The time may go by faster by watching TV or playing a game.
The dose is the same for all patients regardless of weight, age, or other factors
Ask your doctor or Respiratory Therapist for more information about the right way to take TOBI
Information for Patients and Caregivers
TOBI® (Tobramycin Inhalation Solution, USP) is a prescription inhaled medication for cystic fibrosis patients whose lungs contain bacteria called Pseudomonas aeruginosa. TOBI has not been studied in patients under 6 years of age, in those with a lung function outside of a certain range, or in those whose lungs contain bacteria called Burkholderia cepacia. Ask your doctor if TOBI is right for you.
IMPORTANT SAFETY INFORMATION
If you are allergic to antibiotics in the same family as TOBI (ie, aminoglycosides), you should not take TOBI. Tell your doctor before starting treatment if you have any history of hearing, kidney, balance, or muscle problems.
Patients taking TOBI may have temporary side effects like coughing or difficulty breathing.
Some people taking TOBI experienced ringing in the ears, hearing loss, or changes in
voice (hoarseness)
.
Ringing in the ears may be a warning sign for hearing loss. If you
have ringing in the ears, changes in hearing, or dizziness, you should tell your doctor.
In studies, kidney damage was not seen in patients taking TOBI. However, antibiotics in the same family as TOBI have been linked to kidney damage.
If you are pregnant, plan to become pregnant, or if you are breast-feeding, talk with your doctor before taking TOBI.
Some drugs may interact with TOBI. Discuss all medications you are taking with your doctor.
Patients with cystic fibrosis can have many symptoms. Some of these may be related to your medications. You should tell your doctor if you have new or worsening symptoms.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit
www.fda.gov/medwatch, or call 1-800-FDA-1088.
