It's important to have all the facts about taking TOBI® (Tobramycin Inhalation Solution, USP)
.
The questions and answers below are some of those most frequently asked by patients. For additional answers, please contact Novartis at 1-888-NOW-NOVA (1-888-669-6682) or
talk to your doctor.
What kind of air compressor
and nebulizer
should be used when taking TOBI?
The PARI LC® PLUS Reusable Nebulizer and DeVilbiss® Pulmo-Aide®
air compressor should be used when taking TOBI. These are the only
2 pieces of equipment that were tested in TOBI clinical studies.
Can TOBI be mixed with other inhaled medications?
No. TOBI should not be diluted or mixed in the nebulizer with any other medications, including dornase alfa. TOBI should not be diluted with water or saline.
How should TOBI be stored?
Patients should store TOBI ampules in a refrigerator. When there's no refrigerator available, or when transporting TOBI, store the foil pouches (opened or unopened) for up to 28 days at room temperature.
Is TOBI still ok to use if it changes color?
TOBI is clear and slightly yellow. Over time, TOBI's color goes from light yellow to a darker yellow. This is normal as the drug ages, or with changes with temperature or exposure to light. Do not expose TOBI to intense light. When TOBI is exposed to intense light, it will change color from light to dark yellow at a faster rate. It may even become brown with longer exposure. Make sure to store it as recommended.
How should TOBI be incorporated into a treatment routine?
Some patients are on several therapies at once. If taking a bronchodilator, dornase alfa, inhaled steroids, and TOBI, try following this order: bronchodilator first, followed by chest physiotherapy, then other inhaled drugs, and finally TOBI. Ask your Healthcare Professional what is the best treatment regimen for you.
What's the difference between TOBI and compounded IV solutions of tobramycin used for inhalation?
TOBI is the only tobramycin solution approved by the Food and Drug Administration (FDA) for inhalation in patients with cystic fibrosis and Pseudomonas aeruginosa infection. TOBI is free from preservatives . Compounded IV solutions of tobramycin not approved for inhalation by the FDA may not be free from preservatives.
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